Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.50 |
| ▸ | FBP1 | P09467 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895880 | 1.00 | CTSD (0.52) | CTSDHSPD1HSPE1FBP1ALOX15 | |
| SCHEMBL19840133 | 0.83 | MAPT (0.53) | CTSDHSPD1HSPE1FBP1ALOX15 | |
| SCHEMBL12584929 | 0.82 | PDE7A (0.45) | ALDH1A1MAPTKMT2ATSHRITGB2 | |
| SCHEMBL24438715 | 0.80 | CTSD (0.60) | CTSDHSPD1HSPE1FBP1ALOX15 | |
| SCHEMBL2032205 | 0.80 | PPARA (0.46) | CTSDHSPD1HSPE1HSD17B10ALDH1A1 | |
| SCHEMBL2031038 | 0.80 | APP (0.52) | CTSDALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL2035992 | 0.80 | ILK (0.42) | CTSDHSPD1HSPE1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10787996 | 0.79 | CTSD (0.51) | CTSDFBP1ALOX15HSD17B10TDP1 | |
| SCHEMBL24118868 | 0.78 | KMT2A (0.57) | CTSDHSPD1HSPE1TDP1ALDH1A1 | |
| SCHEMBL8563621 | 0.76 | FBP1 (0.58) | CTSDHSPD1HSPE1FBP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395210-A1 | INHIBITION OF BACTERIAL CHAPERONIN SYSTEMS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2021-12-23 | — | — | US | disclosed |
| US-9884046-B1 | Method of treating lung cancer | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395210-A1 | INHIBITION OF BACTERIAL CHAPERONIN SYSTEMS | HSP90B1, HSP90AB1, HSP90AB2P | CTSD 2326/4885HSPD1 21/4885HSPE1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.