Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 7/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840133 | 0.83 | MAPT (0.53) | CTSDHSPD1HSPE1MAPTGAA | |
| SCHEMBL24118877 | 0.80 | CTSD (0.72) | CTSDHSPD1HSPE1MAPTGAA | |
| SCHEMBL19840432 | 0.80 | CTSD (0.52) | CTSDHSPD1HSPE1MAPTGAA | |
| SCHEMBL30895880 | 0.80 | CTSD (0.52) | CTSDHSPD1HSPE1MAPTGAA | |
| SCHEMBL29612961 | 0.79 | HSPD1 (0.69) | CTSDHSPD1HSPE1MAPTGAA | |
| SCHEMBL29612924 | 0.79 | CTSD (0.64) | CTSDHSPD1HSPE1MAPTGAA | |
| SCHEMBL28760743 | 0.79 | HSPD1 (0.69) | CTSDHSPD1HSPE1MAPTGAA | |
| SCHEMBL28760809 | 0.79 | CTSD (0.64) | CTSDHSPD1HSPE1MAPTGAA | |
| SCHEMBL24438054 | 0.78 | MEN1 (0.57) | CTSDHSPD1HSPE1MAPTGAA | |
| SCHEMBL24118857 | 0.78 | HSPD1 (0.78) | CTSDHSPD1HSPE1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103572-A1 | COMPOUNDS AND METHODS OF INHIBITING BACTERIAL CHAPERONIN SYSTEMS | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-05-19 | — | — | WO | disclosed |