Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Azelaic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 9/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimelic Acid SCHEMBL30166508 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL3386429 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL29546221 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL11275273 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Octanedioate SCHEMBL7932891 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL30930282 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL3979911 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Sebacic Acid SCHEMBL2381516 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL7748558 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL106750 | 0.96 | CA1 (0.58) | FABP3CA1FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118615193-A | Cosmetic emulsion with multiple effects and preparation method thereof | 乐普药业科技有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-117442509-A | Low-dosage oil-control allergy-relieving composition and application thereof | 拉芳家化股份有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-115219613-B | Method for detecting azelaic acid and potassium azelate in cosmetics | 上海市食品药品检验研究院 | 2023-12-22 | — | — | CN | claimed |
| CN-116283417-A | Rooting and seedling strengthening agent for China rose seedling transplanting and rooting culture method for China rose seedlings | 东北林业大学 | 2023-06-23 | — | — | CN | claimed |
| CN-114366702-B | Shampoo with effects of removing dandruff, relieving itching and controlling oil and preparation method thereof | 珠海博御中医药研究有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-115381755-A | Anti-allergy acne-removing composition and preparation method thereof | 广州花出见生物科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-114788795-A | Acne-removing composition and preparation method and application thereof | 广州极男化妆品有限公司 | 2022-07-26 | — | — | CN | claimed |
| CN-110638715-B | Men's facial cleanser and preparation method thereof | 广州一一生物技术有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-113398029-B | Antibacterial and anti-dandruff shampoo and preparation method thereof | 珠海博御中医药研究有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-113397994-B | Cosmetic additive and preparation method and application thereof | 珠海博御中医药研究有限公司 | 2022-03-15 | — | — | CN | claimed |
| US-8318786-B2 | Plant pathogen resistance | THE UNIVERSITY OF CHICAGO (US) | 2012-11-27 | — | — | US | claimed |
| JP-2010536785-A | — | — | 2010-12-02 | — | — | JP | claimed |
| EP-2187736-A2 | PLANT PATHOGEN RESISTANCE | The University of Chicago (US) | 2010-05-26 | — | — | EP | claimed |
| WO-2009055126-A2 | PLANT PATHOGEN RESISTANCE | THE UNIVERSITY OF CHICAGO (US) | 2009-04-30 | — | — | WO | claimed |
| US-20090048312-A1 | PLANT PATHOGEN RESISTANCE | THE UNIVERSITY OF CHICAGO (US) | 2009-02-19 | — | — | US | claimed |
| EP-0956572-A4 | HIGH CONDUCTIVITY CROSSLINKED ELECTROLYTE MATERIALS, CAPACITORS INCORPORATING THE SAME AND METHODS OF MAKING THE SAME | TELECTRONICS PACING SYST (US) | 2000-01-26 | — | — | EP | claimed |
| EP-0956572-A1 | HIGH CONDUCTIVITY CROSSLINKED ELECTROLYTE MATERIALS, CAPACITORS INCORPORATING THE SAME AND METHODS OF MAKING THE SAME | Telectronics Pacing Systems, Inc. (US) | 1999-11-17 | — | — | EP | claimed |
| WO-1998006116-A1 | HIGH CONDUCTIVITY CROSSLINKED ELECTROLYTE MATERIALS, CAPACITORS INCORPORATING THE SAME AND METHODS OF MAKING THE SAME | TELECTRONICS PACING SYSTEMS, INC. (US) | 1998-02-12 | — | — | WO | claimed |
| US-5661629-A | High conductivity crosslinked electrolyte materials and capacitors incorporating the same | TELECTRONICS PACING SYSTEMS, INC. | 1997-08-26 | — | — | US | claimed |
| US-4200586-A | Inhibiting the carbon-carbon double bond isomerization of substituted or unsubstituted hydrocarbon compounds | PHILLIPS PETROLEUM COMPANY (US) | 1980-04-29 | — | — | US | claimed |