Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 9/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimelic Acid SCHEMBL30166508 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL3386429 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL29546221 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL11275273 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Octanedioate SCHEMBL7932891 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Azelaic Acid SCHEMBL1984403 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL30930282 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL3979911 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Sebacic Acid SCHEMBL2381516 | 1.00 | FABP3 (0.56) | FABP3CA1FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL106750 | 0.96 | CA1 (0.58) | FABP3CA1FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001294888-A | NON-REUSING TYPE GRINDING FLUID | YUSHIRO CHEM IND CO LTD | 2001-10-23 | — | — | JP | disclosed |
| US-4349625-A | ALBUMIN USING ACYL-COENZYME A SYNTHETASE | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-09-14 | — | — | US | disclosed |