Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18034192 | 0.85 | CA2 (0.36) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL8507597 | 0.85 | THRB (0.38) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| Water SCHEMBL7042206 | 0.84 | CA2 (0.35) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL19844936 | 0.77 | LMNA (0.44) | ALDH1A1LMNAMMP9KDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL9357417 | 0.73 | CA2 (0.56) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL1549893 | 0.70 | ENPP2 (0.50) | — | |
| SCHEMBL19844935 | 0.70 | THRB (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL17278432 | 0.68 | KMT2A (0.46) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5326198 | 0.68 | CA2 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL937040 | 0.67 | LMNA (0.52) | ALDH1A1CYP2C9CYP2C19LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037598-A1 | METHODS OF MAKING AND USING LIGNIN DERIVATIVES | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037598-A1 | METHODS OF MAKING AND USING LIGNIN DERIVATIVES | HLCS, LOX, DCXR | ALDH1A1 247/4885CYP3A4 957/4885CYP2C9 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.