SCHEMBL19848821

SCHEMBL19848821

CN1C(=O)c2cccc(-n3c4ccccc4c4cc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)ccc43)c2C1=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 1/20 0.43
▸ CASP3 P42574 2/20 0.36
▸ MAPT P10636 1/20 0.36
▸ MAPK14 Q16539 2/20 0.35
▸ NPY5R Q15761 1/20 0.35
▸ PTGER4 P35408 4/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ MAOA P21397 1/20 0.34
▸ BRD4 O60885 2/20 0.34
▸ CAMK2D Q13557 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19852605 0.97 ADK (0.45) ADKCASP3MAPTMAPK14MAOA
SCHEMBL23516088 0.94 ADK (0.43) ADKCASP3MAPTMAPK14HSD17B10
SCHEMBL23516093 0.90 ADK (0.45) ADKCASP3MAPTMAPK14MAOA
SCHEMBL19848962 0.88 ADK (0.45) ADKCASP3MAPTBRD4POLB
SCHEMBL23516108 0.86 HSPA1A (0.41) MAPTPTGER4POLBKDM4E
SCHEMBL19848848 0.86 NR1H2 (0.43) CASP3MAPK14HSD17B10POLB
SCHEMBL23516167 0.86 ADK (0.43) ADKCASP3MAPTBRD4POLB
SCHEMBL23516293 0.85 PDE6D (0.45) MAPTPOLBKDM4E
SCHEMBL19843492 0.85 POLB (0.39) CASP3MAPK14HSD17B10POLB
SCHEMBL23516508 0.84 CYP11B2 (0.43) MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11276825-B2 Organic molecules for use in organic devices CYNORA GMBH (DE) 2022-03-15 — — US disclosed
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-17 — — US disclosed
EP-3279193-B1 COMPOUNDS COMPRISING A PHTHALIMIDE GROUP AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-05-08 — — EP disclosed
US-9917270-B1 Organic electroluminescent device having an exciton quenching layer CYNORA GMBH (DE) 2018-03-13 — — US disclosed
US-9917270-B1 Organic electroluminescent device having an exciton quenching layer CYNORA GMBH (DE) 2018-03-13 — — US disclosed
WO-2018024723-A1 PHTHALIMIDE AND CARBAZOLE OR ANALOGS THEREOF CONTAINING COMPOUNDS FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-08 — — WO disclosed
EP-3279193-A1 COMPOUNDS COMPRISING PHTHALIMIDE AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES CHRM1, C1S, DNMT3L ADK 3537/4885CASP3 2113/4885MAPT 4763/4885
US-11276825-B2 Organic molecules for use in organic devices AOX1, OR10J3, L1CAM ADK 3298/4885CASP3 2340/4885MAPT 2595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback