Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.60 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | NAAA | Q02083 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851486 | 1.00 | HPGD (0.62) | HPGDEPHX2FAAHNAAACNR1 | |
| SCHEMBL19851489 | 0.90 | TSHR (0.55) | HPGDEPHX2FAAHCNR1CNR2 | |
| SCHEMBL10380701 | 0.88 | ALDH1A1 (0.50) | HPGDEPHX2FAAHALDH1A1HTT | |
| SCHEMBL19851737 | 0.87 | TLR2 (0.56) | HPGDEPHX2FAAHCNR1CNR2 | |
| SCHEMBL9515447 | 0.85 | EPHX2 (0.72) | HPGDEPHX2FAAHNAAACNR1 | |
| SCHEMBL17117376 | 0.85 | TRPV1 (0.65) | HPGDEPHX2ALDH1A1 | |
| SCHEMBL17117331 | 0.83 | L3MBTL1 (0.68) | HPGDEPHX2EPHX1ALDH1A1 | |
| SCHEMBL9513570 | 0.82 | ALDH1A1 (0.54) | HPGDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL6933592 | 0.82 | CA12 (0.56) | HPGDEPHX2NAAA | |
| Hydrochloric Acid SCHEMBL10610094 | 0.82 | EPHX2 (0.72) | HPGDEPHX2FAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |