Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851489 | 0.88 | TSHR (0.55) | SMN1; SMN2KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL19851737 | 0.83 | TLR2 (0.56) | KDM4ETSHRHPGDRECQLLMNA | |
| SCHEMBL19851687 | 0.82 | HPGD (0.62) | ALDH1A1HPGDHTT | |
| SCHEMBL19851486 | 0.82 | HPGD (0.62) | ALDH1A1HPGDHTT | |
| SCHEMBL10380701 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL17117331 | 0.80 | L3MBTL1 (0.68) | SMN1; SMN2RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL9797532 | 0.79 | ALDH1A1 (0.63) | SMN1; SMN2RAB9AKDM4EALDH1A1MEN1 | |
| SCHEMBL17117376 | 0.79 | TRPV1 (0.65) | SMN1; SMN2ALDH1A1KMT2ATSHRL3MBTL1 | |
| SCHEMBL9513570 | 0.79 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10382127 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |