SCHEMBL19852653

SCHEMBL19852653

CCOCCOC(N)C(=O)CN

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL541064 0.82 ALDH1A1 (0.45) ALDH1A1TSHRTHRB
SCHEMBL788324 0.80 ALDH1A1 (0.43) ALDH1A1TSHRTHRB
Acetic Acid SCHEMBL28822470 0.68 ALDH1A1 (0.58) ALDH1A1TSHRTHRB
SCHEMBL21835936 0.68
Acetic Acid SCHEMBL27325136 0.68 ALDH1A1 (0.58) ALDH1A1TSHRTHRB
SCHEMBL23165292 0.68 CYP1A2 (0.36) ALDH1A1THRB
SCHEMBL15532281 0.68
SCHEMBL14926861 0.67 ALDH1A1 (0.58) ALDH1A1TSHRTHRB
SCHEMBL29219066 0.67 ALDH1A1 (0.42) ALDH1A1TSHRTHRB
SCHEMBL5932911 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10507262-B2 Biocompatible hydrogel treatments for retinal detachment C.P. MEDICAL CORPORATION (US) 2019-12-17 US disclosed
US-20180036452-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES LLC 2018-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180036452-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT ALDH1A2, RB1, UACA ALDH1A1 297/4885TSHR 1883/4885THRB 1990/4885
US-10507262-B2 Biocompatible hydrogel treatments for retinal detachment ALDH1A2, RB1, UACA ALDH1A1 297/4885TSHR 1883/4885THRB 1990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.