Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852722 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2POLBGAA | |
| SCHEMBL28847750 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2POLBGAA | |
| SCHEMBL17150980 | 0.98 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2POLBGAA | |
| SCHEMBL25878264 | 0.87 | — | — | |
| Zinc Ion SCHEMBL2923807 | 0.79 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL13374694 | 0.76 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11737698 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2POLB | |
| Zinc Ion SCHEMBL18786899 | 0.74 | ALDH1A1 (0.32) | ALDH1A1LMNAPOLB | |
| SCHEMBL11733763 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL11301997 | 0.73 | NOS1 (0.42) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037556-A1 | COMPOUNDS AND METHODS FOR INDUCING BROWNING OF WHITE ADIPOSE TISSUE | BEIJING ERAI THERAPEUTICS CO., LTD. (CN) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037556-A1 | COMPOUNDS AND METHODS FOR INDUCING BROWNING OF WHITE ADIPOSE TISSUE | FABP4, LRBA, GPR119 | ALDH1A1 181/4885LMNA 2845/4885SMN1; SMN2 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.