Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24620526 | 0.76 | OTUD7B (0.35) | — | |
| SCHEMBL24339464 | 0.74 | ATM (0.33) | — | |
| SCHEMBL19852942 | 0.74 | GRIN2B (0.38) | GRIN2BGRIN2C | |
| SCHEMBL19852940 | 0.74 | GRIN2B (0.38) | GRIN2BGRIN2C | |
| SCHEMBL24339027 | 0.74 | ALOX15 (0.33) | — | |
| SCHEMBL19852943 | 0.73 | GRIN2B (0.53) | GRIN2BGRIN2C | |
| SCHEMBL19852944 | 0.73 | GRIN2B (0.38) | GRIN2BGRIN2C | |
| SCHEMBL16751001 | 0.72 | GRIN1 (0.32) | GRIN2B | |
| SCHEMBL24339081 | 0.72 | GRIN1 (0.30) | GRIN2B | |
| SCHEMBL19852924 | 0.72 | DRD2 (0.31) | GRIN2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026779-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2018-02-08 | — | — | WO | disclosed |