SCHEMBL19854400

SCHEMBL19854400

C=CC(=O)NCCCc1ccc(OC(F)(F)c2ccc(C3CCC(CCCCC)CC3)cc2)cc1F

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CCR2 P41597 4/20 0.35
▸ CNR2 P34972 3/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ ZDHHC20 Q5W0Z9 1/20 0.34
▸ ZDHHC2 Q9UIJ5 1/20 0.34
▸ CNR1 P21554 2/20 0.33
▸ TEAD1 P28347 1/20 0.33
▸ LSS P48449 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ UBE2M P61081 1/20 0.32
▸ DCUN1D1 Q96GG9 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19855136 0.86 DGAT1 (0.40) CCR2CNR2ALDH1A1LMNAMAPT
SCHEMBL19856060 0.86 LSS (0.37) CNR2ALDH1A1LMNAMAPTTEAD1
SCHEMBL19854539 0.85 CNR2 (0.38) CNR2ZDHHC20ZDHHC2CNR1GAA
SCHEMBL19856042 0.85 ZDHHC20 (0.39) CCR2CNR2ALDH1A1LMNAMAPT
SCHEMBL19722575 0.80 CNR2 (0.33) CNR2ALDH1A1LMNAMAPTCNR1
SCHEMBL19856034 0.79 ZDHHC20 (0.41) CNR2ALDH1A1LMNAMAPTZDHHC20
SCHEMBL7722667 0.79 MAPT (0.36) CNR2ALDH1A1LMNAMAPTGAA
SCHEMBL7722669 0.79 MAPT (0.36) CNR2ALDH1A1LMNAMAPTGAA
SCHEMBL19854520 0.78 SPHK1 (0.47) ALDH1A1LMNAMAPTZDHHC20ZDHHC2
SCHEMBL19854562 0.77 RAB9A (0.47) ALDH1A1LMNAMAPTZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 CCR2 61/4885CNR2 1030/4885ALDH1A1 3826/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 CCR2 61/4885CNR2 1030/4885ALDH1A1 3826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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