SCHEMBL19856460

SCHEMBL19856460

OC[C@H]1O[C@@H](N2CCNCCNCCNCC2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 8/20 0.60
▸ MAPT P10636 1/20 0.40
▸ PYGM P11217 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18851813 1.00 CDA (0.60) CDAMAPTPYGM
SCHEMBL19856471 1.00 CDA (0.60) CDAMAPTPYGM
SCHEMBL31017612 0.88 CDA (0.58) CDAMAPTPYGM
SCHEMBL11707269 0.87 CDA (0.55) CDAMAPT
SCHEMBL11433490 0.82 CDA (0.55) CDAMAPT
SCHEMBL15297983 0.82 CDA (0.55) CDAMAPT
SCHEMBL11114311 0.72 CDA (0.46) CDA
SCHEMBL6976489 0.67 LGALS3 (0.64) —
SCHEMBL16789213 0.67 LGALS3 (0.64) —
SCHEMBL1755358 0.67 LGALS3 (0.64) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200138982-A1 RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY- ACADEMIC COOPERATION FOUNDATION (KR) 2020-05-07 — — US disclosed
US-10583206-B2 Radioactive probe for detecting hydrogen sulfide Kyungpook National University Industry-Academic, Cooperation Foundation (KR) 2020-03-10 — — US disclosed
US-20180369428-A1 RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY- ACADEMIC COOPERATION FOUNDATION (KR) 2018-12-27 — — US disclosed
EP-3281643-A2 RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE Kyungpook National University Industry-Academic Cooperation Foundation (KR) 2018-02-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180369428-A1 RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE TST, CTH, CBS CDA 1221/4885MAPT 3502/4885PYGM 614/4885
US-20200138982-A1 RADIOACTIVE PROBE FOR DETECTING HYDROGEN SULFIDE TST, SCLY, CTH CDA 1375/4885MAPT 3370/4885PYGM 601/4885
US-10583206-B2 Radioactive probe for detecting hydrogen sulfide TST, SCLY, CTH CDA 1375/4885MAPT 3370/4885PYGM 601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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