Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856980 | 1.00 | DRD2 (0.39) | DRD2TAS1R3TAS1R1STAT6DRD4 | |
| SCHEMBL19856908 | 0.92 | ALOX15 (0.40) | DRD2TAS1R3TAS1R1STAT6DRD4 | |
| SCHEMBL19856959 | 0.92 | ALOX15 (0.40) | DRD2TAS1R3TAS1R1STAT6DRD4 | |
| SCHEMBL19856917 | 0.91 | HCRTR1 (0.36) | DRD2TAS1R3TAS1R1STAT6DRD4 | |
| SCHEMBL19856871 | 0.90 | DRD2 (0.41) | DRD2TAS1R3TAS1R1STAT6CYP51A1 | |
| SCHEMBL19856872 | 0.90 | DRD2 (0.41) | DRD2TAS1R3TAS1R1STAT6CYP51A1 | |
| SCHEMBL19856899 | 0.89 | DRD2 (0.41) | DRD2TAS1R3TAS1R1STAT6AKR1C3 | |
| SCHEMBL19856897 | 0.89 | DRD2 (0.41) | DRD2TAS1R3TAS1R1STAT6AKR1C3 | |
| SCHEMBL1549547 | 0.87 | PDGFRB (0.46) | DRD2STAT6AKR1C3NPC1RAB9A | |
| SCHEMBL1549906 | 0.87 | DRD2 (0.42) | DRD2TAS1R3TAS1R1STAT6AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |