Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856908 | 1.00 | ALOX15 (0.40) | ALOX15PYGLDRD4DRD3DRD2 | |
| SCHEMBL19856980 | 0.92 | DRD2 (0.39) | DRD4DRD3DRD2CYP51A1TAS1R3 | |
| SCHEMBL19856978 | 0.92 | DRD2 (0.39) | DRD4DRD3DRD2CYP51A1TAS1R3 | |
| SCHEMBL19856882 | 0.90 | ALOX15 (0.42) | ALOX15PYGLDRD3DRD2CYP51A1 | |
| SCHEMBL19856883 | 0.90 | ALOX15 (0.42) | ALOX15PYGLDRD3DRD2CYP51A1 | |
| SCHEMBL19856896 | 0.89 | PYGL (0.43) | ALOX15PYGLDRD3DRD2CYP51A1 | |
| SCHEMBL19856898 | 0.89 | PYGL (0.43) | ALOX15PYGLDRD3DRD2CYP51A1 | |
| SCHEMBL19856974 | 0.88 | NPC1 (0.42) | ALOX15DRD3DRD2CYP51A1TAS1R3 | |
| SCHEMBL1550025 | 0.87 | PYGL (0.48) | PYGLDRD2CYP51A1SMYD3 | |
| SCHEMBL19856942 | 0.87 | DRD2 (0.42) | ALOX15PYGLDRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |