Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20361417 | 0.75 | CA2 (0.46) | CA2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL18007542 | 0.71 | CA2 (0.40) | CA2KDM4EALDH1A1 | |
| SCHEMBL24131434 | 0.71 | PGR (0.32) | MEN1KMT2ANQO1 | |
| SCHEMBL547874 | 0.70 | MAPT (0.35) | CA2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11055661 | 0.69 | CA2 (0.41) | CA2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6862366 | 0.69 | NLRP3 (0.43) | CA2ALDH1A1CA12CA1CA9 | |
| SCHEMBL19475512 | 0.67 | CA2 (0.37) | CA2ALDH1A1CA12CA1CA9 | |
| SCHEMBL30791028 | 0.66 | ALDH1A1 (0.40) | CA2KDM4EALDH1A1CA12CA1 | |
| SCHEMBL1299014 | 0.65 | KDM4E (0.45) | CA2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19507913 | 0.64 | POLB (0.44) | CA2KDM4EMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044287-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | INFLAZOME LIMITED (IE) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044287-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | NLRP3, PYCARD, IAPP | CA2 2434/4885KDM4E 3179/4885ALDH1A1 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.