Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 14/20 | 0.48 |
| ▸ | CA1 | P00915 | 12/20 | 0.48 |
| ▸ | CA9 | Q16790 | 8/20 | 0.48 |
| ▸ | CA5A | P35218 | 4/20 | 0.48 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17093012 | 0.83 | CA2 (0.52) | CA2CA1CA9CA5ACA6 | |
| SCHEMBL28345243 | 0.83 | CA2 (0.52) | CA2CA1CA9CA5ACA6 | |
| SCHEMBL2069124 | 0.83 | CA2 (0.52) | HSD11B1CA2CA1CA9CA5A | |
| SCHEMBL18802710 | 0.83 | HSD11B1 (0.60) | HSD11B1ALDH1A1TSHRTDP1 | |
| SCHEMBL19475183 | 0.82 | CDK2 (0.43) | HSD11B1CA2CA1CA9CA5A | |
| SCHEMBL19507915 | 0.81 | CDK2 (0.42) | HSD11B1CA2CA1CA9CA5A | |
| SCHEMBL7194865 | 0.81 | CA2 (0.50) | HSD11B1CA2CA1CA9CA5A | |
| SCHEMBL15150588 | 0.81 | HSD11B1 (0.50) | HSD11B1ALDH1A1TSHRTDP1 | |
| SCHEMBL4610078 | 0.81 | STAT3 (0.41) | HSD11B1CA2CA1CA9CA5A | |
| SCHEMBL15924841 | 0.79 | CA2 (0.44) | CA2CA1CA9CA5ACA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044287-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | INFLAZOME LIMITED (IE) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044287-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | NLRP3, PYCARD, IAPP | HSD11B1 4082/4885CA2 2434/4885CA1 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.