Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076165 | 0.93 | CASP2 (0.43) | SLC6A5CASP2FFAR1CPT2TDP1 | |
| SCHEMBL19861218 | 0.89 | ALDH1A1 (0.35) | SLC6A5CASP2FFAR1CPT2TDP1 | |
| SCHEMBL19861156 | 0.82 | CASP2 (0.42) | SLC6A5CASP2NAAAFDPSFAAH | |
| SCHEMBL12334732 | 0.82 | MEN1 (0.35) | SLC6A5CASP2MEN1KMT2AALDH1A1 | |
| SCHEMBL21015900 | 0.82 | FAAH (0.48) | CASP2FFAR1CPT2TDP1NAAA | |
| SCHEMBL23353269 | 0.81 | GNAI3 (0.33) | FFAR1CPT2TDP1DPP7FDPS | |
| SCHEMBL20417363 | 0.81 | CASP2 (0.56) | CASP2FFAR1CPT2TDP1NAAA | |
| SCHEMBL19177310 | 0.80 | CASP2 (0.46) | CASP2FFAR1CPT2TDP1NAAA | |
| SCHEMBL19177042 | 0.79 | FFAR1 (0.37) | CASP2FFAR1CPT2TDP1CCR2 | |
| SCHEMBL1963990 | 0.75 | HPGD (0.42) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |