Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 10/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 4/20 | 0.44 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861654 | 0.83 | ALDH1A1 (0.35) | FOLH1LMNAALDH1A1 | |
| SCHEMBL10602859 | 0.81 | FOLH1 (0.42) | FOLH1NAALAD2RIMKLALMNAMEN1 | |
| SCHEMBL31369710 | 0.81 | TGFBR1 (0.37) | FOLH1NAALAD2RIMKLALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL2982200 | 0.79 | TGFBR1 (0.36) | FOLH1NAALAD2RIMKLALMNAALDH1A1 | |
| SCHEMBL15601969 | 0.77 | FOLH1 (0.50) | FOLH1NAALAD2RIMKLALMNAMEN1 | |
| SCHEMBL24455554 | 0.76 | FOLH1 (0.77) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL13753737 | 0.76 | FOLH1 (0.77) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL21702910 | 0.74 | CHRNB2 (0.38) | FOLH1NAALAD2RIMKLALMNAMEN1 | |
| SCHEMBL1940630 | 0.73 | CTSK (0.46) | MEN1KMT2AMAPT | |
| SCHEMBL14031160 | 0.73 | CTSK (0.46) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9891239-B2 | Modulators of pharmacokinetic properties of therapeutics | GILEAD SCIENCES, INC. (US) | 2018-02-13 | — | — | US | disclosed |