Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.32 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GGH | Q92820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2982200 | 0.98 | TGFBR1 (0.36) | TGFBR1ALDH1A1MAPTDDAH1ABCC4 | |
| Trifluoroacetic Acid SCHEMBL27041508 | 0.89 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL10288381 | 0.88 | MAPT (0.39) | ALDH1A1MAPTDDAH1ABCC4LMNA | |
| SCHEMBL1271960 | 0.88 | MAPT (0.39) | ALDH1A1MAPTDDAH1ABCC4LMNA | |
| SCHEMBL31370342 | 0.86 | MAPT (0.42) | ALDH1A1MAPTDDAH1ABCC4LMNA | |
| SCHEMBL12513863 | 0.85 | MAPT (0.46) | ALDH1A1MAPTDDAH1ABCC4LMNA | |
| SCHEMBL19861653 | 0.81 | FOLH1 (0.44) | TGFBR1ALDH1A1MAPTLMNAFOLH1 | |
| SCHEMBL23561261 | 0.81 | PLA2G2C (0.33) | ALDH1A1LMNAPLA2G2C | |
| SCHEMBL13822050 | 0.81 | ALDH1A1 (0.39) | TGFBR1ALDH1A1MAPTLMNAFOLH1 | |
| SCHEMBL20930337 | 0.81 | ALDH1A1 (0.39) | TGFBR1ALDH1A1MAPTLMNAFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | TGFBR1 3727/4885ALDH1A1 4472/4885MAPT 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.