SCHEMBL19861966

SCHEMBL19861966

Cc1cc(O)cc(C)c1C[C@@H](N)C(=O)NC(CCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 2/20 0.50
▸ OPRD1 P41143 2/20 0.50
▸ OPRK1 P41145 1/20 0.50
▸ NPFFR1 Q9GZQ6 1/20 0.50
▸ NPFFR2 Q9Y5X5 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862065 1.00 OPRM1 (0.50) OPRM1OPRD1OPRK1NPFFR1NPFFR2
SCHEMBL17413435 0.91 CCKBR (0.46) —
SCHEMBL21627096 0.90 CTSL (0.54) OPRM1OPRD1OPRK1NPFFR1NPFFR2
SCHEMBL16862485 0.90 CTSL (0.54) OPRM1OPRD1OPRK1NPFFR1NPFFR2
SCHEMBL19861963 0.90 CTSL (0.54) —
SCHEMBL19862013 0.90 CTSL (0.54) —
Hydrochloric Acid SCHEMBL16862473 0.89 CTSL (0.53) OPRM1OPRD1OPRK1NPFFR1NPFFR2
SCHEMBL19862399 0.88 NPY4R (0.52) OPRM1
SCHEMBL18048887 0.88 NPY4R (0.52) OPRM1
SCHEMBL19862098 0.88 NPY4R (0.52) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides STEALTH BIOTHERAPEUTICS INC. (US) 2024-07-16 — — US disclosed
US-20180044378-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2018-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044378-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD OPRM1 1092/4885OPRD1 1708/4885OPRK1 2236/4885
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides ADM2, VIP, PEPD OPRM1 1092/4885OPRD1 1708/4885OPRK1 2236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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