SCHEMBL17413435

SCHEMBL17413435

Cc1cc(OC(=O)OC(C)(C)C)cc(C)c1C[C@H](N)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 1/20 0.46
▸ REN P00797 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19861966 0.91 OPRM1 (0.50) —
SCHEMBL19862065 0.91 OPRM1 (0.50) —
SCHEMBL17413459 0.89 REN (0.48) CCKBRREN
SCHEMBL23680153 0.83 REN (0.53) CCKBRREN
SCHEMBL17413437 0.83 REN (0.53) CCKBRREN
SCHEMBL17553458 0.83 PAX8 (0.52) CCKBRREN
SCHEMBL21627147 0.82 CTSL (0.51) —
SCHEMBL16870006 0.82 CTSL (0.51) —
SCHEMBL21627096 0.81 CTSL (0.54) —
SCHEMBL16862485 0.81 CTSL (0.54) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3160985-B1 PROCESS FOR THE PRODUCTION OF D-ARGINYL-2,6-DIMETHYL-L-TYROSYL-L-LYSYL-L-PHENYLALANINAMIDE FLAMMA SPA (IT) 2021-07-28 — — EP disclosed
US-20170152289-A1 PROCESS FOR THE PRODUCTION OF D-ARGINYL-2,6-DIMETHYL-L-TYROSYL-L-LYSYL-L-PHENYLALANINAMIDE FLAMMA S.P.A. (IT) 2017-06-01 — — US disclosed
WO-2016001042-A1 PROCESS FOR THE PRODUCTION OF D-ARGINYL-2,6-DIMETHYL-L-TYROSYL-L-LYSYL-L-PHENYLALANINAMIDE FLAMMA S.P.A. (IT) 2016-01-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170152289-A1 PROCESS FOR THE PRODUCTION OF D-ARGINYL-2,6-DIMETHYL-L-TYROSYL-L-LYSYL-L-PHENYLALANINAMIDE ARG2, ARGLU1, ABAT CCKBR 4043/4885REN 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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