Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104801 | 0.89 | LMNA (0.66) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16922505 | 0.85 | LMNA (0.61) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16373471 | 0.85 | LMNA (0.61) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL25491455 | 0.85 | LMNA (0.61) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16376450 | 0.85 | LMNA (0.61) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL18624157 | 0.83 | LMNA (0.57) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL19164369 | 0.82 | MEN1 (0.61) | LMNANPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL19164654 | 0.82 | MEN1 (0.61) | LMNANPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL16376436 | 0.81 | LMNA (0.56) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1104806 | 0.81 | LMNA (0.56) | LMNANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2020-06-23 | — | — | US | disclosed |
| US-20180155312-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-06-07 | — | — | US | disclosed |
| US-20180159045-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-06-07 | — | — | US | disclosed |
| US-20180047907-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
| US-20180047918-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | ESRRA, REN, ESRRB | LMNA 3761/4885NPC1 3562/4885RAB9A 495/4885 |
| US-20180047918-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | ORC3, AOX1, RCOR3 | LMNA 4731/4885NPC1 4499/4885RAB9A 450/4885 |
| US-20180047907-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | CNKSR1, CBX4, RBX1 | LMNA 4344/4885NPC1 4226/4885RAB9A 482/4885 |
| US-20180155312-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | SOD1, SCO2, RCOR3 | LMNA 4698/4885NPC1 4753/4885RAB9A 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.