Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 5/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16491009 | 0.81 | KISS1R (0.54) | KISS1RANPEPHDAC7HDAC8HDAC6 | |
| SCHEMBL8976208 | 0.81 | CA1 (0.36) | KISS1RFOLH1ANPEPENPEP | |
| SCHEMBL9977108 | 0.80 | HDAC7 (0.52) | KISS1RHDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL24162078 | 0.77 | CA2 (0.52) | KISS1RHDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL13347954 | 0.75 | KISS1R (0.46) | KISS1R | |
| SCHEMBL19862678 | 0.75 | — | — | |
| SCHEMBL2868532 | 0.75 | FOLH1 (0.41) | KISS1RFOLH1ANPEPENPEPHDAC7 | |
| SCHEMBL13311767 | 0.75 | — | — | |
| SCHEMBL9977109 | 0.75 | — | — | |
| SCHEMBL16328006 | 0.74 | CPB2 (0.45) | KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210154306-A1 | DEGRADABLE THIOL-ENE POLYMERS AND METHODS OF MAKING THEREOF | MOSAIC BIOSCIENCES, INC. | 2021-05-27 | — | — | US | disclosed |
| US-10912837-B2 | Degradable thiol-ene polymers and methods of making thereof | MOSAIC BIOSCIENCES, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| US-20180043030-A1 | DEGRADABLE THIOL-ENE POLYMERS AND METHODS OF MAKING THEREOF | MOSAIC BIOSCIENCES, INC. | 2018-02-15 | — | — | US | disclosed |
| US-20180043030-A1 | DEGRADABLE THIOL-ENE POLYMERS AND METHODS OF MAKING THEREOF | MOSAIC BIOSCIENCES, INC. | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180043030-A1 | DEGRADABLE THIOL-ENE POLYMERS AND METHODS OF MAKING THEREOF | CTH, AHCY, PTMS | KISS1R 3620/4885FOLH1 1288/4885ANPEP 22/4885 |
| US-10912837-B2 | Degradable thiol-ene polymers and methods of making thereof | CTH, AHCY, PTMS | KISS1R 3620/4885FOLH1 1288/4885ANPEP 22/4885 |
| US-20210154306-A1 | DEGRADABLE THIOL-ENE POLYMERS AND METHODS OF MAKING THEREOF | CTH, AHCY, PTMS | KISS1R 3620/4885FOLH1 1288/4885ANPEP 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.