Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19862696 | 0.79 | — | — | |
| SCHEMBL6130647 | 0.76 | MEN1 (0.32) | TDP1 | |
| SCHEMBL17715092 | 0.70 | ALDH1A1 (0.36) | TDP1ALDH1A1 | |
| SCHEMBL10122626 | 0.69 | HSD17B10 (0.36) | TDP1 | |
| SCHEMBL24594830 | 0.68 | CYP1A2 (0.31) | — | |
| SCHEMBL16865882 | 0.67 | DGKA (0.37) | ALDH1A1HPGDPLA2G4B | |
| SCHEMBL17981497 | 0.67 | — | — | |
| SCHEMBL25511754 | 0.67 | — | — | |
| SCHEMBL17407254 | 0.67 | ALDH1A1 (0.54) | TDP1ALDH1A1HPGD | |
| SCHEMBL11238183 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180043030-A1 | DEGRADABLE THIOL-ENE POLYMERS AND METHODS OF MAKING THEREOF | MOSAIC BIOSCIENCES, INC. | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180043030-A1 | DEGRADABLE THIOL-ENE POLYMERS AND METHODS OF MAKING THEREOF | CTH, AHCY, PTMS | TDP1 1492/4885ALDH1A1 2090/4885HPGD 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.