Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 7/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992542 | 0.95 | KIF11 (0.37) | NR1H3NR1H2KIF11TSHRCA12 | |
| SCHEMBL20059347 | 0.90 | P2RX4 (0.40) | NR1H3NR1H2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL20059322 | 0.89 | NR1H3 (0.34) | NR1H3NR1H2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL15458044 | 0.88 | ALDH1A1 (0.35) | NR1H3NR1H2KIF11TSHRCA12 | |
| SCHEMBL29313199 | 0.88 | NR1H2 (0.36) | NR1H3NR1H2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL13864781 | 0.88 | NR1H2 (0.35) | NR1H3NR1H2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL14932219 | 0.85 | P2RX4 (0.38) | NR1H3NR1H2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL16940872 | 0.84 | HDAC4 (0.38) | MAPTSMN1; SMN2NPSR1P2RX4KIF11 | |
| SCHEMBL14934590 | 0.84 | CA12 (0.37) | NR1H3NR1H2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL14934596 | 0.83 | AHR (0.42) | NR1H3NR1H2MAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12041848-B2 | Heterocyclic compound and organic light emitting element comprising same | LG CHEM, LTD. (KR) | 2024-07-16 | — | — | US | disclosed |
| US-10981876-B2 | Spiro compound and organic light emitting element comprising same | LG CHEM, LTD. | 2021-04-20 | — | — | US | disclosed |
| US-10968230-B2 | Spiro-structured compound and organic electronic device comprising same | LG CHEM, LTD. | 2021-04-06 | — | — | US | disclosed |
| US-10230056-B2 | Heterocyclic compound and organic light emitting element comprising same | LG CHEM, LTD. (KR) | 2019-03-12 | — | — | US | disclosed |
| US-20180175304-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-06-21 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20180047914-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-02-15 | — | — | US | disclosed |
| US-20180047914-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10230056-B2 | Heterocyclic compound and organic light emitting element comprising same | CRY1, CRY2, NR2E3 | NR1H3 681/4885NR1H2 634/4885MAPT 746/4885 |
| US-12041848-B2 | Heterocyclic compound and organic light emitting element comprising same | CRY1, CRY2, NR2E3 | NR1H3 681/4885NR1H2 634/4885MAPT 746/4885 |
| US-20180175304-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, ERG | NR1H3 51/4885NR1H2 57/4885MAPT 893/4885 |
| US-20180047914-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | CRY1, CRY2, NR2E3 | NR1H3 681/4885NR1H2 634/4885MAPT 746/4885 |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, ERG | NR1H3 51/4885NR1H2 57/4885MAPT 893/4885 |
| US-10968230-B2 | Spiro-structured compound and organic electronic device comprising same | ESR1, OR10J3, ERG | NR1H3 383/4885NR1H2 342/4885MAPT 1988/4885 |
| US-10981876-B2 | Spiro compound and organic light emitting element comprising same | RER1, RIF1, CRY1 | NR1H3 91/4885NR1H2 90/4885MAPT 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.