SCHEMBL19863245

SCHEMBL19863245

COc1ccccc1C(=O)C(C)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.48
ALDH1A1 P00352 1/20 0.48
CTSD P07339 1/20 0.47
XBP1 P17861 1/20 0.47
NPC1 O15118 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MAOB P27338 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
STAT3 P40763 1/20 0.45
KCNK3 O14649 2/20 0.45
KCNK9 Q9NPC2 2/20 0.45
RAB9A P51151 2/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
HTT P42858 2/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31318924 0.80 CTSD (0.55) HPGDALDH1A1CTSDXBP1NPC1
SCHEMBL31257134 0.80 CTSD (0.55) HPGDALDH1A1CTSDXBP1NPC1
SCHEMBL4303504 0.80 CTSD (0.55) HPGDALDH1A1CTSDXBP1NPC1
SCHEMBL27860086 0.79 HPGD (0.50) HPGDALDH1A1CTSDXBP1NPC1
SCHEMBL19863247 0.77 HPGD (0.41) HPGDALDH1A1NPC1SMN1; SMN2RAB9A
SCHEMBL9041066 0.77 CTSD (0.56) HPGDALDH1A1CTSDXBP1NPC1
SCHEMBL2339959 0.77 CTSD (0.51) HPGDALDH1A1CTSDXBP1NPC1
SCHEMBL8441866 0.77 CTSD (0.55) HPGDALDH1A1CTSDXBP1NPC1
SCHEMBL7055752 0.76 KMT2A (0.54) HPGDALDH1A1CTSDXBP1NPC1
SCHEMBL19863249 0.76 LMNA (0.51) ALDH1A1GAAKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-9951164-B2 Non-ionic aryl ketone based polymeric photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS PFAS, PLG, PPARG HPGD 1822/4885ALDH1A1 888/4885CTSD 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.