SCHEMBL19863247

SCHEMBL19863247

Cc1ccccc1C(=O)C(C)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
ERCC5 P28715 1/20 0.40
FEN1 P39748 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
HTT P42858 1/20 0.39
ALDH1A1 P00352 1/20 0.38
ALOX12 P18054 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PDK2 Q15119 1/20 0.37
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
PIK3CD O00329 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21173780 0.83 SLC6A2 (0.42) HPGDSLC6A2SLC6A4SLC6A3ERCC5
SCHEMBL19863249 0.80 LMNA (0.51) SLC6A2SLC6A4ALDH1A1
SCHEMBL19863246 0.79 NFE2L2 (0.40) NPC1RAB9AHTTALDH1A1ALOX12
SCHEMBL19863244 0.79 NR4A1 (0.52) HPGDNPC1RAB9AALDH1A1ADRB2
SCHEMBL585832 0.78 HPGD (0.47) HPGDSLC6A2SLC6A4SLC6A3ERCC5
SCHEMBL19863245 0.77 HPGD (0.48) HPGDNPC1RAB9AHTTALDH1A1
SCHEMBL1685076 0.76 HPGD (0.46) HPGDSLC6A2SLC6A4SLC6A3ERCC5
SCHEMBL32665936 0.76 HPGD (0.46) HPGDSLC6A2SLC6A4SLC6A3ERCC5
SCHEMBL14297428 0.76 HPGD (0.46) HPGDSLC6A2SLC6A4SLC6A3ERCC5
SCHEMBL2233660 0.76 HPGD (0.48) HPGDSLC6A2SLC6A4SLC6A3ERCC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-9951164-B2 Non-ionic aryl ketone based polymeric photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS PFAS, PLG, PPARG HPGD 1822/4885SLC6A2 4578/4885SLC6A4 3074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.