SCHEMBL1986471

SCHEMBL1986471

CCCCCCCCCCCC(=O)NCCOCCOCCN

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 2/20 0.55
FAAH O00519 4/20 0.54
DNM1 Q05193 2/20 0.51
LPAR1 Q92633 2/20 0.50
LPAR2 Q9HBW0 2/20 0.50
TLR2 O60603 2/20 0.50
CASP2 P42575 1/20 0.50
ENPP2 Q13822 1/20 0.50
GLP1R P43220 3/20 0.47
NAAA Q02083 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3139392 1.00 SLC6A5 (0.55) SLC6A5FAAHDNM1LPAR1LPAR2
SCHEMBL26032972 1.00 SLC6A5 (0.55) SLC6A5FAAHDNM1LPAR1LPAR2
SCHEMBL26032397 1.00 SLC6A5 (0.55) SLC6A5FAAHDNM1LPAR1LPAR2
SCHEMBL25735688 1.00 SLC6A5 (0.55) SLC6A5FAAHDNM1LPAR1LPAR2
SCHEMBL1987159 1.00 SLC6A5 (0.55) SLC6A5FAAHDNM1LPAR1LPAR2
SCHEMBL1988266 0.98 SLC6A5 (0.56) SLC6A5FAAHDNM1LPAR1LPAR2
SCHEMBL16524092 0.98 SLC6A5 (0.56) SLC6A5FAAHDNM1LPAR1LPAR2
SCHEMBL20856400 0.98 SLC6A5 (0.56) SLC6A5FAAHDNM1LPAR1LPAR2
SCHEMBL17817133 0.98 SLC6A5 (0.56) SLC6A5FAAHDNM1LPAR1LPAR2
SCHEMBL25067294 0.97 SLC6A5 (0.52) SLC6A5FAAHDNM1LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180311316-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2018-11-01 US claimed
US-20170182131-A9 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2017-06-29 US claimed
US-9493583-B2 Anionic polysaccharides functionalized by a hydrophobic acid derivative ADOCIA (FR) 2016-11-15 US claimed
EP-2741765-B9 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN ADOCIA (FR) 2016-09-28 EP claimed
EP-3053590-A1 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN Adocia (FR) 2016-08-10 EP claimed
EP-2741765-B1 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN ADOCIA (FR) 2016-03-30 EP claimed
US-20150250858-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2015-09-10 US claimed
US-9089476-B2 Injectable solution at pH 7 comprising at least one basal insulin whose PI is between 5.8 and 8.5 ADOCIA (FR) 2015-07-28 US claimed
EP-2741765-A1 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN Adocia (FR) 2014-06-18 EP claimed
US-20130065826-A1 Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 ADOCIA (FR) 2013-03-14 US claimed
WO-2013021143-A1 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN ADOCIA (FR) 2013-02-14 WO claimed
EP-2516473-B1 ANIONIC POLYSACCHARIDES FUNCTIONALISED WITH A DERIVATIVE OF HYDROPHOBIC ACID ADOCIA (FR) 2020-09-30 EP disclosed
US-10449256-B2 Injectable solution at pH 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer ADOCIA (FR) 2019-10-22 US disclosed
US-20180311316-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 ADOCIA (FR) 2018-11-01 US disclosed
US-20180169249-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN THE ISOELECTRIC POINT OF WHICH IS BETWEEN 5.8 AND 8.5 AND A HYDROPHOBIZED ANIONIC POLYMER ADOCIA (FR) 2018-06-21 US disclosed
US-20130065826-A1 Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 ADOCIA (FR) 2013-03-14 US disclosed
WO-2013021143-A1 INJECTABLE SOLUTION OF AT LEAST ONE TYPE OF BASAL INSULIN ADOCIA (FR) 2013-02-14 WO disclosed
EP-2516473-A1 ANIONIC POLYSACCHARIDES FUNCTIONALISED BY A HYDROPHOBIC ACID DERIVATIVE Adocia (FR) 2012-10-31 EP disclosed
US-20110172166-A1 Anionic polysaccharides functionalized by a hydrophobic acid derivative ADOCIA (FR) 2011-07-14 US disclosed
WO-2011077405-A1 ANIONIC POLYSACCHARIDES FUNCTIONALISED BY A HYDROPHOBIC ACID DERIVATIVE ADOCIA (FR) 2011-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170182131-A9 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 IAPP, IGFBP5, INSR SLC6A5 481/4885FAAH 4107/4885DNM1 938/4885
US-20110172166-A1 Anionic polysaccharides functionalized by a hydrophobic acid derivative ALG1, CD44, FUT6 SLC6A5 1565/4885FAAH 3193/4885DNM1 4329/4885
US-20180311316-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 IAPP, IGFBP5, INSR SLC6A5 481/4885FAAH 4107/4885DNM1 938/4885
US-20150250858-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHOSE PI IS BETWEEN 5.8 AND 8.5 IAPP, IGFBP5, INSR SLC6A5 481/4885FAAH 4107/4885DNM1 938/4885
US-20180169249-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN THE ISOELECTRIC POINT OF WHICH IS BETWEEN 5.8 AND 8.5 AND A HYDROPHOBIZED ANIONIC POLYMER IAPP, IGFBP5, IDE SLC6A5 1388/4885FAAH 3264/4885DNM1 3060/4885
US-10449256-B2 Injectable solution at pH 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer IAPP, IGFBP5, IDE SLC6A5 1388/4885FAAH 3264/4885DNM1 3060/4885
US-20130065826-A1 Injectable solution at pH 7 Comprising at least one basal insulin whose PI is between 5.8 and 8.5 IAPP, IGFBP5, INSR SLC6A5 481/4885FAAH 4107/4885DNM1 938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.