Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954266 | 0.81 | GLA (0.48) | CYP19A1BCHESLC6A3SIGMAR1ALDH1A1 | |
| SCHEMBL2575793 | 0.80 | LOXL2 (0.64) | LOXL2CYP2A6CYP19A1TSHRHSD17B10 | |
| SCHEMBL20824910 | 0.79 | SMN1; SMN2 (0.50) | HSD17B10BCHESIGMAR1KCNH2TMEM97 | |
| SCHEMBL9127520 | 0.77 | KCNH2 (0.59) | BCHESLC6A3SIGMAR1KCNH2TMEM97 | |
| SCHEMBL21799832 | 0.77 | SIGMAR1 (0.43) | BCHESIGMAR1KCNH2TMEM97ALDH1A1 | |
| SCHEMBL172531 | 0.77 | SIGMAR1 (0.66) | BCHESIGMAR1KDM4E | |
| Hydrochloric Acid SCHEMBL27619587 | 0.75 | SIGMAR1 (0.63) | BCHESIGMAR1KDM4EMEN1KMT2A | |
| SCHEMBL25588023 | 0.75 | ALDH1A1 (0.44) | TSHRBCHESIGMAR1KCNH2TMEM97 | |
| SCHEMBL172666 | 0.75 | MEN1 (0.61) | BCHEALDH1A1MEN1KMT2A | |
| SCHEMBL25588047 | 0.75 | MEN1 (0.61) | BCHEALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044343-A1 | BICYCLIC IMIDAZOLO DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044343-A1 | BICYCLIC IMIDAZOLO DERIVATIVE | PDE3A, PDE2A, PDE5A | LOXL2 3377/4885CYP2A6 1879/4885CYP19A1 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.