SCHEMBL19880

SCHEMBL19880

NS(=O)(=O)c1cc[c]cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 0.55
CA1 P00915 15/20 0.55
CA9 Q16790 14/20 0.55
CA12 O43570 13/20 0.55
CA5A P35218 9/20 0.55
CA7 P43166 8/20 0.55
CA5B Q9Y2D0 8/20 0.55
CA4 P22748 7/20 0.55
CA6 P23280 6/20 0.55
CA14 Q9ULX7 6/20 0.55
CA13 Q8N1Q1 3/20 0.55
CA3 P07451 3/20 0.55
PLA2G7 Q13093 1/20 0.55
USP2 O75604 1/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
AGO2 Q9UKV8 1/20 0.52
ALDH1A1 P00352 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28835117 1.00 CA2 (0.55) CA2CA1CA9CA12CA5A
SCHEMBL28022329 0.95 CA2 (0.50) CA2CA1CA9CA12CA5A
Benzenesulfonamide SCHEMBL27357661 0.91 CA2 (0.73) CA2CA1CA9CA12CA5A
SCHEMBL27491694 0.85 CA2 (0.73) CA2CA1CA9CA12CA5A
SCHEMBL28554532 0.79 SOS1 (0.56) CA2CA1CA9CA12CA5A
SCHEMBL202948 0.78 CA2 (0.81) CA2CA1CA9CA12CA5A
SCHEMBL818508 0.77 HTR6 (0.50) TSHRALDH1A1
Benzenesulfonamide SCHEMBL1009443 0.74 CA2 (0.94) CA2CA1CA9CA12CA5A
SCHEMBL600074 0.72 ALDH1A1 (0.55) TDP1ALDH1A1
SCHEMBL20194 0.72 ENPP2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4198 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133860-A1 SYNTHESIS OF SMALL MOLECULE AGONISTS OF NEUROPTROPHIN Oculis Operations Sàrl (CH) 2024-06-27 WO claimed
US-20240122941-A1 THERAPY BASED ON SYNTHETIC LETHALITY IN SWI/SNF COMPLEX-DYSFUNCTION CANCER NATIONAL CANCER CENTER (JP) 2024-04-18 US claimed
US-20240116903-A1 TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2024-04-11 US claimed
WO-2023249105-A1 THERAPEUTIC AGENT OR PREVENTIVE AGENT FOR DRUG-INDUCED MYOCARDIAL DISORDERS 東レ株式会社 2023-12-28 WO claimed
WO-2023249107-A1 THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR PERIPHERAL NERVE DISORDER 東レ株式会社 2023-12-28 WO claimed
WO-2023249106-A1 THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS 東レ株式会社 2023-12-28 WO claimed
EP-4295852-A2 PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) Syros Pharmaceuticals, Inc. (US) 2023-12-27 EP claimed
WO-2023230217-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 WO claimed
US-20230381142-A1 ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-11-30 US claimed
CN-117126118-A Synthesis method of celecoxib 上海应用技术大学 2023-11-28 CN claimed
US-4275201-A Aryl substituted diketones STERLING DRUG INC. (US) 1981-06-23 US claimed
US-4247479-A REACTING THE OXIME HYDROCHLORIDE WITH THREE MOLES OF ACETIC ANHYDRIDE HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-27 US claimed
US-4246284-A Aminosulfonyl-substituted aryloxyalkyl diketones STERLING DRUG INC. (US) 1981-01-20 US claimed
EP-0022141-A1 Compositions and methods for reducing herbicidal injury MONSANTO COMPANY (US) 1981-01-14 EP claimed
EP-0011048-A1 A process for the manufacture of substantially pure 3-amino-4-alkoxy-acylanilides from 2,4-dinitrochlorobenzene Toms River Chemical Corporation (US) 1980-05-14 EP claimed
US-RE29358-E ANTI-MALARIA AND ANTI-TUBERCULOSIS AGENTS AMERICAN CYANAMID COMPANY (US) 1977-08-16 US claimed
US-4024123-A TEXTILES DUSSY PAUL 1977-05-17 US claimed
US-4001204-A Magenta image-providing phenylazonaphthyl dues containing a morpholinyl of piperidine radical EASTMAN KODAK COMPANY (US) 1977-01-04 US claimed
US-3954476-A Diffusable dye-releasing compounds which are cleavable upon oxidation EASTMAN KODAK COMPANY (US) 1976-05-04 US claimed
US-3932380-A DIFFUSION TRANSFER COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1976-01-13 US claimed