SCHEMBL19880331

SCHEMBL19880331

Ic1ccc(Cc2c3ccccc3c(Cc3ccc(I)cc3)c3ccccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
APP P05067 8/20 0.42
CYP3A4 P08684 2/20 0.38
IDO1 P14902 2/20 0.38
CALM1 P0DP23 1/20 0.38
VKORC1 Q9BQB6 1/20 0.33
NQO1 P15559 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
SNCA P37840 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1841464 0.79 CALM1 (0.61) IDO1CALM1NQO1KDM4EALDH1A1
SCHEMBL4511 0.77 CALM1 (0.67) APPCYP3A4IDO1CALM1ALDH1A1
SCHEMBL982996 0.76 P2RX4 (0.43) IDO1KDM4EALDH1A1CYP1A2
SCHEMBL3186379 0.76 ESR1 (0.59)
SCHEMBL5491719 0.76 CYP3A4 (0.50) APPCYP3A4IDO1CALM1ALDH1A1
SCHEMBL9440191 0.73 TAAR1 (0.40) APPCYP3A4IDO1
SCHEMBL17996024 0.73 SMN1; SMN2 (0.48) CALM1KDM4EALDH1A1
SCHEMBL9306794 0.71 CALM1 (0.57) APPCYP3A4IDO1CALM1ALDH1A1
SCHEMBL19880351 0.71 IDH1 (0.44) IDO1NQO1CYP1A2
SCHEMBL984055 0.71 LTA4H (0.67) IDO1VKORC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9896535-B2 Epoxy compound having alkoxysilyl group, method of preparing the same, composition and cured product comprising the same, and uses thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-20 US disclosed