Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306794 | 0.93 | CALM1 (0.57) | CALM1APPLTA4HIDH1PLA2G10 | |
| SCHEMBL5491719 | 0.88 | CYP3A4 (0.50) | CALM1APPALDH1A1CYP3A4IDO1 | |
| SCHEMBL972712 | 0.85 | CALM1 (0.92) | CALM1LTA4HIDH1PLA2G10PLA2G2A | |
| SCHEMBL8094422 | 0.85 | CALM1 (0.92) | CALM1LTA4HIDH1PLA2G10PLA2G2A | |
| SCHEMBL11445053 | 0.83 | ALDH1A1 (0.57) | APPALDH1A1HPGDALOX15ALOX12 | |
| Hydrochloric Acid SCHEMBL27978245 | 0.82 | CALM1 (0.86) | CALM1LTA4HIDH1PLA2G10PLA2G2A | |
| Diphenylmethane SCHEMBL3792579 | 0.82 | CALM1 (1.00) | CALM1LTA4HIDH1PLA2G10PLA2G2A | |
| Diphenylmethane SCHEMBL4361124 | 0.82 | CALM1 (1.00) | CALM1LTA4HIDH1PLA2G10PLA2G2A | |
| Diphenylmethane SCHEMBL14763944 | 0.82 | CALM1 (1.00) | CALM1LTA4HIDH1PLA2G10PLA2G2A | |
| Diphenylmethane SCHEMBL1303 | 0.82 | CALM1 (1.00) | CALM1LTA4HIDH1PLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085300-B | Modified polybutadiene resin and preparation method and application thereof | 南亚新材料科技股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-114085300-A | Modified polybutadiene resin and preparation method and application thereof | 南亚新材料科技股份有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-119241747-A | Supported nickel catalyst and method for catalyzing ethylene polymerization | 陕西煤业化工技术研究院有限责任公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20240425504-A1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (assignee) (JP) | 2024-12-26 | — | — | US | disclosed |
| EP-3808747-B1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL (JP) | 2024-12-18 | — | — | EP | disclosed |
| US-12077531-B2 | Imidazopyridinone compound | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2024-09-03 | — | — | US | disclosed |
| CN-112689637-B | Imidazopyridone compounds | 橘生药品工业株式会社 | 2023-11-10 | — | — | CN | disclosed |
| CN-114085300-A | Modified polybutadiene resin and preparation method and application thereof | 南亚新材料科技股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| US-20210206765-A1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-07-08 | — | — | US | disclosed |
| EP-3808747-A1 | IMIDAZOPYRIDINONE COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-04-21 | — | — | EP | disclosed |
| CN-112689637-A | Imidazopyridinone compounds | 橘生药品工业株式会社 | 2021-04-20 | — | — | CN | disclosed |
| US-20030092769-A1 | DIARYL-ENYNES | NPS ALLELIX CORPORATION (CA) | 2003-05-15 | — | — | US | disclosed |
| US-6525085-B2 | Treating neurological and neuropsychiatric disorders | NPS ALLELIX CORP. (CA) | 2003-02-25 | — | — | US | disclosed |
| CN-1387507-A | diaryl enynes | NPS ALLELIX CORP (CA) | 2002-12-25 | — | — | CN | disclosed |
| US-20020169197-A1 | Diaryl-enynes | NPS ALLELIX CORP. | 2002-11-14 | — | — | US | disclosed |
| EP-1226108-A1 | DIARYL-ENYNES | NPS Allelix Corp. (CA) | 2002-07-31 | — | — | EP | disclosed |
| US-6426364-B1 | NERVOUS SYSTEM OR PSYCHOLOGICAL DISORDERS | NPS ALLELIX CORP. (CA) | 2002-07-30 | — | — | US | disclosed |
| CN-1304400-A | Novel substituted cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-07-18 | — | — | CN | disclosed |
| CN-1300277-A | Novel substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-20 | — | — | CN | disclosed |
| WO-2001032602-A1 | DIARYL-ENYNES | NPS ALLELIX CORP. (CA) | 2001-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12077531-B2 | Imidazopyridinone compound | EGLN3, DHPS, EGLN2 | CALM1 2398/4885APP 4075/4885LTA4H 323/4885 |
| US-20240425504-A1 | IMIDAZOPYRIDINONE COMPOUND | EGLN3, DHPS, EGLN2 | CALM1 2398/4885APP 4075/4885LTA4H 323/4885 |
| US-20210206765-A1 | IMIDAZOPYRIDINONE COMPOUND | DHPS, EGLN3, P4HA1 | CALM1 2518/4885APP 4105/4885LTA4H 422/4885 |
| US-20020169197-A1 | Diaryl-enynes | CBR3, CNR1, NR3C2 | CALM1 1893/4885APP 4065/4885LTA4H 947/4885 |
| US-20030092769-A1 | DIARYL-ENYNES | CBR3, CNR1, CBR1 | CALM1 1885/4885APP 4068/4885LTA4H 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.