Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.52 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668968 | 0.87 | TGM2 (0.65) | TGM2RAB9ACREBBPLMNAMEN1 | |
| SCHEMBL39036 | 0.85 | TGM2 (0.72) | TGM2L3MBTL1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL1925142 | 0.83 | KMT2A (0.71) | TGM2RAB9ATDP1NPSR1CREBBP | |
| SCHEMBL4103284 | 0.82 | TGM2 (0.76) | TGM2LMNAEGFR | |
| SCHEMBL8686781 | 0.82 | PARP1 (0.68) | TGM2MEN1KMT2A | |
| SCHEMBL12096453 | 0.81 | L3MBTL1 (0.68) | L3MBTL1GAARAB9ABLMATM | |
| SCHEMBL81209 | 0.80 | TGM2 (1.00) | TGM2NPSR1LMNAEGFR | |
| SCHEMBL19501282 | 0.80 | TGM2 (0.76) | TGM2RAB9AMAPTLMNAMEN1 | |
| SCHEMBL7745302 | 0.80 | KCNK3 (0.79) | L3MBTL1GAARAB9ABLMTDP1 | |
| SCHEMBL28847032 | 0.79 | KMT2A (0.58) | TGM2GAAALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190293641-A1 | ASSAY | IMPERIAL COLLEGE INNOVATIONS, LTD. (GB) | 2019-09-26 | — | — | US | disclosed |
| WO-2018033753-A2 | ASSAY | IMPERIAL INNOVATIONS LIMITED (GB) | 2018-02-22 | — | — | WO | disclosed |