SCHEMBL1989999

SCHEMBL1989999

CCCCCC(N)c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
TLR8 Q9NR97 1/20 0.43
CNR2 P34972 3/20 0.40
KDM4E B2RXH2 2/20 0.39
KMT2A Q03164 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CNR1 P21554 3/20 0.39
IKBKB O14920 1/20 0.38
ALOX15 P16050 2/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
RCE1 Q9Y256 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1678986 0.99 ALOX5 (0.43) ALOX5TLR8CNR2KDM4EKMT2A
SCHEMBL1990198 0.99 ALOX5 (0.43) ALOX5TLR8CNR2KDM4EKMT2A
SCHEMBL8915580 0.99 ALOX5 (0.43) ALOX5TLR8CNR2KDM4EKMT2A
SCHEMBL1994555 0.99 ALOX5 (0.43) ALOX5TLR8CNR2KDM4EKMT2A
SCHEMBL1990279 0.95 ALOX5 (0.45) ALOX5TLR8CNR2CNR1IKBKB
SCHEMBL1992949 0.89 ALOX5 (0.47) ALOX5TLR8CNR2ALDH1A1
SCHEMBL4800205 0.86 SLC2A1 (0.44) CNR2KDM4EKMT2AL3MBTL1CNR1
SCHEMBL9312708 0.83 ALDH1A1 (0.44) KMT2AALDH1A1GAA
SCHEMBL12342225 0.82 KDM4E (0.44) ALOX5TLR8CNR2KDM4EKMT2A
SCHEMBL6900194 0.79 SLC2A1 (0.48) TLR8KDM4EKMT2AL3MBTL1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2055764-B1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD AND USE OF THE LUBRICANT AOKI SCIENCE INST CO LTD (JP) 2014-10-15 EP disclosed
US-8841242-B2 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2014-09-23 US disclosed
US-8728994-B2 Oil type lubricant for forging, forging method and spray apparatus AOKI SCIENCE INSTITUTE CO., LTD. (JP) 2014-05-20 US disclosed
EP-2520638-A1 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2012-11-07 EP disclosed
US-20110152145-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-06-23 US disclosed
EP-2177594-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-04-21 EP disclosed
US-20090118149-A1 Oil Type Lubricant for Forging, Forging Method and Spray Apparatus AOKI SCIENCES INSTITUTE CO.,LTD. (JP) 2009-05-07 US disclosed
EP-2055764-A1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD, AND COATING APPARATUS Aoki Science Institute Co, Ltd (JP) 2009-05-06 EP disclosed
US-20060252659-A1 Lubricating oil for dynamic fluid-pressure bearing, dynamic-fluid-pressure bearing, motor, and information recording/reproducing apparatus SEIKO INSTRUMENTS, INC. (JP) 2006-11-09 US disclosed
US-6586376-B1 Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2003-07-01 US disclosed
US-6191080-B1 MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS TONEN CORPORATION (JP) 2001-02-20 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed