SCHEMBL8915580

SCHEMBL8915580

CCCCCCCCCCCC(N)c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.43
TLR8 Q9NR97 1/20 0.42
KDM4E B2RXH2 4/20 0.41
KMT2A Q03164 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CNR1 P21554 2/20 0.40
CNR2 P34972 1/20 0.39
NPC1 O15118 3/20 0.38
ALDH1A1 P00352 3/20 0.38
GAA P10253 3/20 0.38
HTT P42858 3/20 0.38
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1678986 1.00 ALOX5 (0.43) ALOX5TLR8KDM4EKMT2AL3MBTL1
SCHEMBL1990198 1.00 ALOX5 (0.43) ALOX5TLR8KDM4EKMT2AL3MBTL1
SCHEMBL1994555 1.00 ALOX5 (0.43) ALOX5TLR8KDM4EKMT2AL3MBTL1
SCHEMBL1989999 0.99 ALOX5 (0.44) ALOX5TLR8KDM4EKMT2AL3MBTL1
SCHEMBL1990279 0.94 ALOX5 (0.45) ALOX5TLR8CNR1CNR2ALDH1A1
SCHEMBL1992949 0.88 ALOX5 (0.47) ALOX5TLR8CNR2ALDH1A1CYP1A2
SCHEMBL4800205 0.88 SLC2A1 (0.44) KDM4EKMT2AL3MBTL1CNR1CNR2
SCHEMBL12342225 0.84 KDM4E (0.44) ALOX5TLR8KDM4EKMT2AL3MBTL1
SCHEMBL9312708 0.82 ALDH1A1 (0.44) KMT2AALDH1A1GAACYP1A2CYP2C19
Tetradecane SCHEMBL9931525 0.81 CNR1 (0.51) TLR8KDM4EKMT2ACNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104204169-A Grease composition and rolling device JTEKT CORP 2014-12-10 CN disclosed
CN-104204175-A Grease composition and rolling device JTEKT CORP 2014-12-10 CN disclosed
CN-101486942-B Metal working oil NIPPON OIL CORP 2012-10-03 CN disclosed
CN-1896152-B Photostabilizer emulsified composition ADEKA CORP 2011-07-20 CN disclosed
CN-101035883-B Oil composition for cutting/grinding process of trace oil supply type NIPPON OIL CORP 2010-10-27 CN disclosed
CN-100584932-C metal working oil NIPPON OIL CORP 2010-01-27 CN disclosed
CN-100523149-C Metalworking fluid NIPPON OIL CORP (JP) 2009-08-05 CN disclosed
CN-101486942-A Metal working oil NIPPON OIL CORP (JP) 2009-07-22 CN disclosed
CN-101035883-A Oil composition for cutting/grinding process of trace oil supply type NIPPON OIL CORP (JP) 2007-09-12 CN disclosed
CN-1922293-A metal working oil NIPPON OIL CORP (JP) 2007-02-28 CN disclosed
CN-1906278-A Metalworking fluid NIPPON OIL CORP (JP) 2007-01-31 CN disclosed
CN-1896152-A Photostabilizer emulsified composition ADEKA CORP (JP) 2007-01-17 CN disclosed
US-5658866-A OXIDATION RESISTANCE; SLUDGE INHIBITING NIPPON OIL CO., LTD. (JP) 1997-08-19 US disclosed
EP-0716141-A2 Lubricating oil compositions NIPPON OIL Co. Ltd. (JP) 1996-06-12 EP disclosed