SCHEMBL1992949

SCHEMBL1992949

CCCC(N)c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.47
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
SLC6A4 P31645 1/20 0.38
TLR8 Q9NR97 1/20 0.37
AOC3 Q16853 1/20 0.37
CNR2 P34972 1/20 0.36
HTR7 P34969 1/20 0.36
DHFR P00374 1/20 0.36
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
METAP2 P50579 2/20 0.35
METAP1 P53582 2/20 0.35
PTPN1 P18031 1/20 0.35
FDPS P14324 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1990279 0.91 ALOX5 (0.45) ALOX5ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL1989999 0.89 ALOX5 (0.44) ALOX5ALDH1A1TLR8CNR2
SCHEMBL1678986 0.88 ALOX5 (0.43) ALOX5ALDH1A1CYP1A2CYP2C19TLR8
SCHEMBL8915580 0.88 ALOX5 (0.43) ALOX5ALDH1A1CYP1A2CYP2C19TLR8
SCHEMBL1994555 0.88 ALOX5 (0.43) ALOX5ALDH1A1CYP1A2CYP2C19TLR8
SCHEMBL1990198 0.88 ALOX5 (0.43) ALOX5ALDH1A1CYP1A2CYP2C19TLR8
SCHEMBL29484443 0.86 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL9313554 0.86 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL28109983 0.78 ALOX5 (0.56) ALOX5ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL9312708 0.77 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2055764-B1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD AND USE OF THE LUBRICANT AOKI SCIENCE INST CO LTD (JP) 2014-10-15 EP disclosed
US-8841242-B2 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2014-09-23 US disclosed
US-8728994-B2 Oil type lubricant for forging, forging method and spray apparatus AOKI SCIENCE INSTITUTE CO., LTD. (JP) 2014-05-20 US disclosed
EP-2520638-A1 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2012-11-07 EP disclosed
US-20110152145-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-06-23 US disclosed
EP-2177594-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-04-21 EP disclosed
US-20090118149-A1 Oil Type Lubricant for Forging, Forging Method and Spray Apparatus AOKI SCIENCES INSTITUTE CO.,LTD. (JP) 2009-05-07 US disclosed
EP-2055764-A1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD, AND COATING APPARATUS Aoki Science Institute Co, Ltd (JP) 2009-05-06 EP disclosed
US-20060252659-A1 Lubricating oil for dynamic fluid-pressure bearing, dynamic-fluid-pressure bearing, motor, and information recording/reproducing apparatus SEIKO INSTRUMENTS, INC. (JP) 2006-11-09 US disclosed