SCHEMBL1990279

SCHEMBL1990279

CCCCC(N)c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.45
TLR8 Q9NR97 1/20 0.41
IKBKB O14920 1/20 0.41
CNR2 P34972 1/20 0.40
CNR1 P21554 2/20 0.36
SLC6A4 P31645 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ALOX15 P16050 1/20 0.36
AOC3 Q16853 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1989999 0.95 ALOX5 (0.44) ALOX5TLR8IKBKBCNR2CNR1
SCHEMBL1678986 0.94 ALOX5 (0.43) ALOX5TLR8IKBKBCNR2CNR1
SCHEMBL8915580 0.94 ALOX5 (0.43) ALOX5TLR8IKBKBCNR2CNR1
SCHEMBL1990198 0.94 ALOX5 (0.43) ALOX5TLR8IKBKBCNR2CNR1
SCHEMBL1994555 0.94 ALOX5 (0.43) ALOX5TLR8IKBKBCNR2CNR1
SCHEMBL1992949 0.91 ALOX5 (0.47) ALOX5TLR8CNR2SLC6A4ALDH1A1
SCHEMBL9312708 0.87 ALDH1A1 (0.44) SLC6A4ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL4800205 0.81 SLC2A1 (0.44) CNR2CNR1SLC6A4ALDH1A1CYP1A2
SCHEMBL12342225 0.78 KDM4E (0.44) ALOX5TLR8CNR2CNR1CYP1A2
SCHEMBL9313554 0.77 ALDH1A1 (0.47) SLC6A4ALDH1A1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230166635-A1 MONITORING HEALTH OF HEAT TRANSFER FLUIDS FOR ELECTRIC SYSTEMS ExxonMobil Technology and Engineering Company (US) 2023-06-01 US disclosed
US-9359573-B2 Migration of air release in lubricant base stocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-07 US disclosed
EP-2055764-B1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD AND USE OF THE LUBRICANT AOKI SCIENCE INST CO LTD (JP) 2014-10-15 EP disclosed
US-8841242-B2 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2014-09-23 US disclosed
US-8728994-B2 Oil type lubricant for forging, forging method and spray apparatus AOKI SCIENCE INSTITUTE CO., LTD. (JP) 2014-05-20 US disclosed
US-20140038867-A1 MIGRATION OF AIR RELEASE IN LUBRICANT BASE STOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-02-06 US disclosed
EP-2520638-A1 Anti-wear agent, additive composition for lubricant, and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2012-11-07 EP disclosed
US-20110152145-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-06-23 US disclosed
EP-2177594-A1 ANTI-WEAR AGENT, ADDITIVE COMPOSITION FOR LUBRICANT, AND LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-04-21 EP disclosed
US-20090286455-A1 METHOD FOR SIZING SINTERED METAL IDEMITSU KOSAN CO., LTD. (JP) 2009-11-19 US disclosed
US-20090118149-A1 Oil Type Lubricant for Forging, Forging Method and Spray Apparatus AOKI SCIENCES INSTITUTE CO.,LTD. (JP) 2009-05-07 US disclosed
EP-2055764-A1 OIL-BASED LUBRICANT FOR FORGING, FORGING METHOD, AND COATING APPARATUS Aoki Science Institute Co, Ltd (JP) 2009-05-06 EP disclosed
US-20060252659-A1 Lubricating oil for dynamic fluid-pressure bearing, dynamic-fluid-pressure bearing, motor, and information recording/reproducing apparatus SEIKO INSTRUMENTS, INC. (JP) 2006-11-09 US disclosed
US-6586376-B1 Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2003-07-01 US disclosed
US-6191080-B1 MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS TONEN CORPORATION (JP) 2001-02-20 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed