SCHEMBL19901944

SCHEMBL19901944

COCN1CC(OC(=O)c2cc(C(CC(C)C)C(C)C)cc3ccccc23)CN(COC)C1=O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 17/20 0.38
HTR3B O95264 17/20 0.38
HTR3A P46098 17/20 0.38
HTR3D Q70Z44 17/20 0.38
HTR3C Q8WXA8 17/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10053085 0.86 HTR3E (0.38) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL19901950 0.81 HTR3A (0.32) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10053075 0.79 HTR3E (0.35) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10053071 0.78 HDAC4 (0.33) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10053079 0.74 ALDH1A1 (0.34) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10053080 0.73 TP53 (0.31) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10053086 0.73 TP53 (0.31) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10053072 0.73 HTR3E (0.35) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL19901949 0.72 RAB9A (0.40)
SCHEMBL10053070 0.72 HDAC4 (0.33) HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9904168-B2 Actinic ray-sensitive or radiation-sensitive resin composition, actinic ray-sensitive or radiation-sensitive film, mask blank provided with actinic ray-sensitive or radiation-sensitive film, pattern forming method, method for manufacturing electronic device, and electronic device FUJIFILM CORPORATION (JP) 2018-02-27 US disclosed