SCHEMBL19901949

SCHEMBL19901949

COCN1CC(OC(=O)COc2ccc(C(CC(C)C)C(C)C)cc2)CN(COC)C1=O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 3/20 0.38
POLB P06746 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
ACACB O00763 3/20 0.34
GAA P10253 1/20 0.33
FKBP1A P62942 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15978740 0.85 ALDH1A1 (0.49) RAB9ASMN1; SMN2MAPTALDH1A1POLB
SCHEMBL19901948 0.83 POLB (0.37) SMN1; SMN2ALDH1A1POLBKMT2AMEN1
SCHEMBL17936660 0.79 RAB9A (0.45) RAB9ASMN1; SMN2MAPTALDH1A1POLB
SCHEMBL20109662 0.77 POLB (0.34) POLBKMT2AMEN1
SCHEMBL19901978 0.76 HTR3E (0.33)
SCHEMBL18356147 0.75 TDP1 (0.44) RAB9ASMN1; SMN2ALDH1A1KMT2AMEN1
SCHEMBL18356832 0.74 ALDH1A1 (0.51) RAB9ASMN1; SMN2MAPTALDH1A1POLB
SCHEMBL19901944 0.72 HTR3E (0.38)
SCHEMBL20109663 0.72 POLB (0.46) RAB9ASMN1; SMN2ALDH1A1POLBKMT2A
SCHEMBL12459475 0.70 PTPN1 (0.43) RAB9ASMN1; SMN2MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9904168-B2 Actinic ray-sensitive or radiation-sensitive resin composition, actinic ray-sensitive or radiation-sensitive film, mask blank provided with actinic ray-sensitive or radiation-sensitive film, pattern forming method, method for manufacturing electronic device, and electronic device FUJIFILM CORPORATION (JP) 2018-02-27 US disclosed