Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19902755 | 0.90 | KMT2A (0.43) | NAMPTMAPTBRAFRAB9ANPC1 | |
| SCHEMBL19902740 | 0.76 | GRM4 (0.46) | BLMNAMPTCSF1RMAPTKCNJ6 | |
| SCHEMBL19902783 | 0.73 | SGMS2 (0.35) | NAMPTL3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL19902767 | 0.71 | RAB9A (0.44) | NAMPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL16489237 | 0.70 | MEN1 (0.45) | NAMPTL3MBTL1CSF1RMAPTGRM4 | |
| SCHEMBL13616257 | 0.68 | GAA (0.62) | BLMNAMPTL3MBTL1BRAFRAB9A | |
| SCHEMBL29824559 | 0.67 | MEN1 (0.55) | BLMNAMPTCSF1RMAPTGRM4 | |
| SCHEMBL15886346 | 0.67 | TSHR (0.69) | L3MBTL1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL11004089 | 0.66 | TDP1 (0.42) | L3MBTL1MAPTKDM4E | |
| SCHEMBL4127751 | 0.65 | RAB9A (0.56) | BLMCSF1RMAPTGRM4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3033337-B1 | SUBSTITUTED IMIDAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS | JANSSEN PHARMACEUTICA NV (BE) | 2018-02-28 | — | — | EP | disclosed |