Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16115868 | 0.86 | L3MBTL1 (0.53) | KMT2AMAPTL3MBTL1TDP1MPO | |
| SCHEMBL16140804 | 0.82 | MAPT (0.50) | KMT2AMAPTL3MBTL1TDP1MPO | |
| SCHEMBL28699689 | 0.82 | KMT2A (0.55) | KMT2AMAPTL3MBTL1TDP1MPO | |
| SCHEMBL30474518 | 0.82 | KMT2A (0.55) | KMT2AMAPTL3MBTL1TDP1MPO | |
| SCHEMBL17518823 | 0.80 | MPO (0.51) | KMT2AMAPTL3MBTL1TDP1MPO | |
| SCHEMBL12844296 | 0.78 | MPO (0.49) | KMT2AMAPTL3MBTL1TDP1MPO | |
| SCHEMBL16140868 | 0.78 | L3MBTL1 (0.48) | KMT2AMAPTL3MBTL1TDP1MPO | |
| SCHEMBL12775844 | 0.77 | MPO (0.48) | KMT2AMAPTL3MBTL1TDP1MPO | |
| SCHEMBL28099592 | 0.75 | MPO (0.47) | KMT2AMAPTL3MBTL1TDP1MPO | |
| SCHEMBL11841355 | 0.75 | MAPT (0.53) | KMT2AMAPTL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2989100-B1 | NAPHTHYRIDINE DERIVATIVES USEFUL AS ALPHA-V-BETA-6 INTEGRIN ANTAGONISTS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2018-02-28 | — | — | EP | disclosed |