Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17518823 | 0.81 | MPO (0.51) | MPOKMT2AMAPTL3MBTL1TDP1 | |
| SCHEMBL30474518 | 0.80 | KMT2A (0.55) | MPOKMT2AMAPTL3MBTL1TDP1 | |
| SCHEMBL28699689 | 0.80 | KMT2A (0.55) | MPOKMT2AMAPTL3MBTL1TDP1 | |
| SCHEMBL12844296 | 0.79 | MPO (0.49) | MPOKMT2AMAPTL3MBTL1TDP1 | |
| SCHEMBL16115868 | 0.78 | L3MBTL1 (0.53) | MPOKMT2AMAPTL3MBTL1TDP1 | |
| SCHEMBL12775844 | 0.78 | MPO (0.48) | MPOKMT2AMAPTL3MBTL1TDP1 | |
| SCHEMBL3160394 | 0.77 | MAPT (0.45) | KMT2AMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL19902885 | 0.75 | KMT2A (0.54) | MPOKMT2AMAPTL3MBTL1TDP1 | |
| SCHEMBL16140804 | 0.75 | MAPT (0.50) | MPOKMT2AMAPTL3MBTL1TDP1 | |
| SCHEMBL16726987 | 0.75 | MAPT (0.47) | MPOKMT2AMAPTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189499-B | naphthyridine derivatives useful as avbeta6 integrin antagonists | 葛兰素史克知识产权开发有限公司 | 2016-09-28 | — | — | CN | disclosed |