Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474518 | 1.00 | KMT2A (0.55) | KMT2AMPOMAPTL3MBTL1TDP1 | |
| SCHEMBL17518823 | 0.85 | MPO (0.51) | KMT2AMPOMAPTL3MBTL1TDP1 | |
| SCHEMBL12844296 | 0.83 | MPO (0.49) | KMT2AMPOMAPTL3MBTL1TDP1 | |
| SCHEMBL19902885 | 0.82 | KMT2A (0.54) | KMT2AMPOMAPTL3MBTL1TDP1 | |
| SCHEMBL16115868 | 0.82 | L3MBTL1 (0.53) | KMT2AMPOMAPTL3MBTL1TDP1 | |
| SCHEMBL12775844 | 0.81 | MPO (0.48) | KMT2AMPOMAPTL3MBTL1TDP1 | |
| SCHEMBL28099592 | 0.80 | MPO (0.47) | KMT2AMPOMAPTL3MBTL1TDP1 | |
| SCHEMBL16140804 | 0.79 | MAPT (0.50) | KMT2AMPOMAPTL3MBTL1TDP1 | |
| SCHEMBL2616605 | 0.78 | KDM4E (0.50) | KMT2AMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL30516210 | 0.78 | KDM4E (0.50) | KMT2AMAPTL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354635-B | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113354635-A | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2021-09-07 | — | — | CN | disclosed |