SCHEMBL19903787

SCHEMBL19903787

CCCCNC(=O)CCSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.52
L3MBTL1 Q9Y468 2/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.45
KIF11 P52732 4/20 0.45
CYP2C9 P11712 1/20 0.45
HSD17B10 Q99714 1/20 0.44
EPHX2 P34913 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23299724 0.92 KIF11 (0.47) HPGDL3MBTL1HTTKIF11
SCHEMBL23299715 0.86 LMNA (0.52) HPGDL3MBTL1TSHRKIF11
SCHEMBL2806972 0.85 L3MBTL1 (0.43) HPGDL3MBTL1TSHRKIF11
SCHEMBL16330567 0.84 EPHX2 (0.48) HPGDKIF11EPHX2
SCHEMBL18704727 0.83 KIF11 (0.42) HPGDKIF11
SCHEMBL18704720 0.83 KIF11 (0.56) KIF11
SCHEMBL23299714 0.82 HDAC6 (0.41) HPGDL3MBTL1TSHRKIF11
SCHEMBL99144 0.82 HDAC6 (0.50) TSHR
SCHEMBL3158110 0.81 HDAC3 (0.46) HPGDL3MBTL1KIF11
SCHEMBL18023229 0.81 L3MBTL1 (0.40) HPGDL3MBTL1ALDH1A1TSHRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2949665-B1 GLYCOSYLATION ATRIAL NATRIURETIC PEPTIDE DAIICHI SANKYO CO LTD (JP) 2018-02-28 EP disclosed