Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 5/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23299715 | 0.88 | LMNA (0.52) | L3MBTL1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL99144 | 0.86 | HDAC6 (0.50) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL19903787 | 0.85 | HPGD (0.52) | L3MBTL1TSHRHPGDKIF11 | |
| SCHEMBL9978090 | 0.84 | LMNA (0.48) | L3MBTL1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL6909931 | 0.83 | L3MBTL1 (0.46) | L3MBTL1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL23299724 | 0.82 | KIF11 (0.47) | L3MBTL1LMNAHPGDKIF11 | |
| SCHEMBL18704720 | 0.82 | KIF11 (0.56) | KIF11 | |
| SCHEMBL23299714 | 0.81 | HDAC6 (0.41) | L3MBTL1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL4139067 | 0.81 | SMN1; SMN2 (0.43) | LMNAHPGDKIF11 | |
| SCHEMBL3158110 | 0.80 | HDAC3 (0.46) | L3MBTL1HDAC6HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475685-B2 | Particle and near-field optical waveguide | KABUSHIKI KAISHA TOSHIBA (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20100239219-A1 | PARTICLE AND NEAR-FIELD OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239219-A1 | PARTICLE AND NEAR-FIELD OPTICAL WAVEGUIDE | F2, AHR, CRY1 | L3MBTL1 2946/4885HDAC6 4144/4885HDAC1 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.