Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903853 | 0.82 | MAOB (0.56) | NPC1RAB9ATDP1MAOBMAOA | |
| SCHEMBL19984615 | 0.81 | MAOB (0.61) | NPC1RAB9ATDP1MAOBMAOA | |
| SCHEMBL19984677 | 0.75 | RXRA (0.57) | MAOBCHRM3SMN1; SMN2KMT2A | |
| SCHEMBL435043 | 0.75 | ALDH1A1 (0.61) | ERN1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL6690276 | 0.74 | ALDH1A1 (0.65) | ERN1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL1134404 | 0.72 | ALDH1A1 (0.54) | ERN1NPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL27749976 | 0.72 | CASR (0.53) | TDP1KMT2A | |
| SCHEMBL5885604 | 0.71 | ALDH1A1 (0.68) | ERN1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL25222497 | 0.71 | TUBB1 (0.55) | ERN1TUBB1NPC1RAB9ATDP1 | |
| SCHEMBL16697221 | 0.70 | RAB9A (0.46) | ERN1NPC1RAB9ATDP1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928890-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |