Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906329 | 0.94 | KDM4E (0.36) | MAP4K4PTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19905802 | 0.91 | MAP4K4 (0.43) | MAP4K4PTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906059 | 0.88 | KDM4E (0.33) | MAP4K4PTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906249 | 0.85 | ALDH1A1 (0.43) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906236 | 0.83 | PTGDR2 (0.38) | MAP4K4PTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906247 | 0.83 | ABL1 (0.40) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17547144 | 0.82 | PTGDR2 (0.35) | MAP4K4PTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906269 | 0.82 | EIF4E (0.40) | MAP4K4PTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906287 | 0.82 | KDR (0.37) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15341117 | 0.82 | MAP4K4 (0.37) | MAP4K4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |