Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | DVL1 | O14640 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906195 | 0.94 | CASP3 (0.37) | PTGDR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL19905936 | 0.89 | KDM4E (0.32) | PTGDR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL19906111 | 0.88 | PTGER3 (0.38) | PTGDR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL19905990 | 0.86 | GRM5 (0.39) | PTGDR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL19906127 | 0.86 | FABP4 (0.36) | PTGDR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL19906003 | 0.85 | TRIM24 (0.41) | PTGDR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL19906287 | 0.83 | KDR (0.37) | PTGDR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL19905858 | 0.83 | USP2 (0.38) | PTGDR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL19906079 | 0.83 | ACVR1B (0.40) | — | |
| SCHEMBL19906193 | 0.83 | CASP3 (0.33) | PTGDR2KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |