SCHEMBL1990656

SCHEMBL1990656

CCCCCCCCCCCCCCCCCC(=O)C(C)(C(=O)CCCCCCCCCCCCCCCCC)C(C)(O)NC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 11/20 0.50
▸ CES1 P23141 10/20 0.50
▸ CES2 O00748 5/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ HSP90AA1 P07900 1/20 0.42
▸ GPR84 Q9NQS5 2/20 0.42
▸ PPARG P37231 2/20 0.42
▸ PPARD Q03181 2/20 0.42
▸ PPARA Q07869 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ SLC22A6 Q4U2R8 1/20 0.42
▸ SLC22A8 Q8TCC7 1/20 0.42
▸ TLR2 O60603 1/20 0.42
▸ HDAC11 Q96DB2 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL874333 1.00 FAAH (0.50) FAAHCES1CES2MEN1CYP1A2
SCHEMBL16515965 0.89 APAF1 (0.46) FAAHCES1CES2MEN1CYP1A2
Hydrochloric Acid SCHEMBL28919223 0.77 FAAH (0.53) FAAHCES1CES2MEN1CYP1A2
SCHEMBL455073 0.77 FAAH (0.53) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2410991 0.77 FAAH (0.53) FAAHCES1CES2MEN1CYP1A2
Ammonia Solution, Strong SCHEMBL30906594 0.76 FAAH (0.57) FAAHCES1CES2MEN1CYP1A2
Ammonia Solution, Strong SCHEMBL31070821 0.76 FAAH (0.57) FAAHCES1CES2MEN1CYP1A2
Dimethylamine SCHEMBL745789 0.76 FAAH (0.57) FAAHCES1CES2MEN1CYP1A2
SCHEMBL14546387 0.76 FAAH (0.61) FAAHCES1CES2MEN1CYP1A2
SCHEMBL15967394 0.76 FAAH (0.61) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11890365-B2 Composition and process for treating hair L'OREAL (FR) 2024-02-06 — — US disclosed
US-9827178-B2 Composition containing a volatile linear alkane, an aminated silicone and a vegetable oil L'OREAL (FR) 2017-11-28 — — US disclosed
EP-2701673-B1 DYE COMPOSITION USING A PARTICULAR PHENOLIC COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES L'ORÉAL (FR) 2017-09-13 — — EP disclosed
EP-2338466-B1 Cosmetic composition containing at least one volatile linear alkane, at least one amine silicone having a particular content, and at least one vegetable oil L'ORÉAL (FR) 2017-03-08 — — EP disclosed
US-9241886-B2 Dye composition using a particular phenolic coupler in a medium rich in fatty substances, processes and devices L'OREAL (FR) 2016-01-26 — — US disclosed
EP-2701673-A1 DYE COMPOSITION USING A PARTICULAR PHENOLIC COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES L'Oréal (FR) 2014-03-05 — — EP disclosed
US-20140053346-A1 DYE COMPOSITION USING A PARTICULAR PHENOLIC COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES L'OREAL (FR) 2014-02-27 — — US disclosed
US-20130280199-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE HYGROSCOPIC SALT, AT LEAST ONE AROMATIC POLYOL ETHER AND AT LEAST ONE DIOL, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2013-10-24 — — US disclosed
WO-2012146529-A1 DYE COMPOSITION USING A PARTICULAR PHENOLIC COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES L'OREAL (FR) 2012-11-01 — — WO disclosed
WO-2012080224-A2 NON-SILICONE COMPOSITION COMPRISING A SCLEROGLUCAN GUM AND A PARTICULAR SURFACTANT L'OREAL (FR) 2012-06-21 — — WO disclosed
EP-2338468-A1 Cosmetic composition comprising at least one volatile linear alkane, at least one cationic surfactant whereby the two components are in a specific ratio L'Oréal (FR) 2011-06-29 — — EP disclosed
EP-2338467-A1 Cosmetic composition including at least one volatile linear alkane, at least one silicone and at least one glyceride with a specific ratio of glyceride to silicone L'Oréal (FR) 2011-06-29 — — EP disclosed
EP-2338466-A1 Cosmetic composition containing at least one volatile linear alkane, at least one amine silicone having a particular content, and at least one vegetable oil L'Oréal (FR) 2011-06-29 — — EP disclosed
US-20110150786-A1 COMPOSITION CONTAINING A VOLATILE LINEAR ALKANE, AN AMINATED SILICONE AND A VEGETABLE OIL L'OREAL (FR) 2011-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11890365-B2 Composition and process for treating hair TYR, NACA, TST FAAH 834/4885CES1 3061/4885CES2 2368/4885
US-20130280199-A1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE HYGROSCOPIC SALT, AT LEAST ONE AROMATIC POLYOL ETHER AND AT LEAST ONE DIOL, AND COSMETIC TREATMENT PROCESS KRT18, DSG1, H1-0 FAAH 765/4885CES1 3435/4885CES2 3125/4885
US-20110150786-A1 COMPOSITION CONTAINING A VOLATILE LINEAR ALKANE, AN AMINATED SILICONE AND A VEGETABLE OIL KRT18, VIM, ALK FAAH 457/4885CES1 4078/4885CES2 3132/4885
US-20140053346-A1 DYE COMPOSITION USING A PARTICULAR PHENOLIC COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES C1R, F12, AKR1C3 FAAH 501/4885CES1 527/4885CES2 771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback